Conquering Diseases

A Follow On Study for People with Ulcerative Colitis Who Joined Earlier Studies of SHP647


Seeking participants of the SHP647-301 or SHP647-302 studies for Ulcerative Colitis. This follow on study tests two amounts (doses) of the drug by monthly injection compared with a fake medicine (placebo).


Participants of this study will get monthly injections with either 25mg or 75mg of the study drug or a placebo (fake injection) for one year. You do not choose or know what dose, if any, you receive. Any side effects and benefits will be noted by patient report and through tests like blood draws, physical exam by the study doctor and examination of the colon by endoscopy.

What we're hoping for

To learn if the study drug, SHP647, works to treat moderate to severe Ulcerative Colitis and is safe for the patient compared with no treatment (placebo).

Additional Information Identifier: NCT03290781

 Principal Investigator

JeanMarie  Houghton, MD, PhD

University of Massachusetts Medical School

 Study Contact

The Gastrointestinal Research  Office



UMMS University Campus

55 Lake Ave North 

Worcester,MA 01655