Conquering Diseases

Study Of An Experimental Drug To Prevent Recurrent Clostridium Difficile Infection


Seeking men and women with a clostridium difficile infection (CDI), also called C. Difficile or C. Diff, that has returned at least once for a study to see if an experimental drug is better than nothing in preventing additional episodes of CDI.


We are studying whether an experimental drug containing bacteria grown in clean conditions and put into capsules can help improve the health of volunteer's intestinal bacteria and if this reduces the chance of CDI returning. About half of the volunteers will get a capsule with the experimental drug and half will get a capsule that does not contain any active medication (placebo). Neither the researcher or the volunteers will know who is getting the experimental drug.

What we're hoping for

We hope that the experimental drug will reduce the chances of volunteers having another clostridium difficile infection.

Additional Information Identifier: NCT03788434

 Principal Investigator

JeanMarie  Houghton, MD, PhD

University of Massachusetts Medical School

 Study Contact

Anne  Foley


UMMS University Campus

55 Lake Ave North 

Worcester,MA 01655