Conquering Diseases

Can We Improve Treatment For Blocked Arteries Using Tools That Are Already On The Cath Lab Shelf?


Seeking adult patients whose doctor has ordered a test called a Cardiac Catheterization to check for and possibly fix blockages in the heart. The doctor performing the cardiac catheterization will decide which patients who volunteer for the study are suitable participants.


When arteries in the heart become blocked, chest pain or a heart attack can occur. The blockage is often due to build up of Plaque. Your doctor may open the artery with balloons and Stents. When the plaque contains calcium it can be very hard. The doctor may decide to pre-treat this calcified plaque using a small drill (atherectomy) to thin out the plaque before using the balloon and stent. None of the devices or procedures used in this trial are experimental. Follow up by phone call.

What we're hoping for

In this study we are trying to learn if it is better or not to treat certain types of heart blockages with a special drill (orbital atherectomy) to thin out calcified plaque in the blocked artery before using the balloon and stent.

Additional Information Identifier: NCT03108546

 Principal Investigator

Nikolaos  Kakouros, MD

UMass Memorial Health

 Study Contact

Cardiovascular Research Office

(508) 856-1014


UMass Chan University Campus

55 Lake Ave North 

Worcester,MA 01655