Conquering Diseases

A Study Comparing Pre-Surgical Treatment In Patients With Localized Kidney Cancer (Prosper Rcc)

Description

Seeking adults with localized (has not spread) kidney cancer who plan to undergo surgery to remove all or part of their kidney (nephrectomy) for a study comparing treatment with or without an investigational immunotherapy drug before surgery

Overview

This study compares treatment with or without an investigational drug (nivolumab) before surgery to remove all or part of a kidney (nephrectomy) in treating patients with kidney cancer that has not spread to other areas of the body. The investigational drug may help the body's immune system attack the cancer and prevent tumor cells from growing and spreading. It is not yet known whether treatment before surgery is more effective than surgery alone in treating patients with kidney cancer.

What we're hoping for

We hope that giving the investigational drug, nivolumab, before kidney or part of a kidney removal surgery (nephrectomy) may make the tumor smaller and reduce the amount of normal tissue to be removed in patients with localized kidney cancer.

Additional Information

ClinicalTrials.gov Identifier: NCT03055013

 Principal Investigator

Kriti  Mittal, MD, MS

UMass Memorial Health

 Study Contact

The Cancer  Research Office

508-856-3216

Cancer.research@umassmed.edu

 Location

UMass Chan University Campus

55 Lake Ave North 

Worcester,MA 01655

508-856-8989