Conquering Diseases

Study of Treatment of Moderate to Severe Ulcerative Colitis (Pfizer Vibrato)


Seeking volunteers age 18-75 years with Moderate to Severe Ulcerative Colitis to test two investigational medications to see if they are more effective than a pill that has no medication in it (placebo) at treating Ulcerative Colitis.


Participants will be given a daily pill with one of two investigational drugs or a pill with no medication in it (placebo) to find out whether the investigational drugs are safe and/ or effective for treating Ulcerative Colitis. Initially you will not be told what medication is in your daily pill. After 8 weeks everyone will get the investigational drug.

What we're hoping for

To find safe and effective new treatments for people with Ulcerative Colitis .

Additional Information Identifier: NCT02958865

 Principal Investigator

JeanMarie  Houghton, MD, PhD

University of Massachusetts Medical School

 Study Contact

The Gastrointestinal Research  Office



UMMS University Campus

55 Lake Ave North 

Worcester,MA 01655