Conquering Diseases

Investigational Study For Prostate Cancer In Males Getting Radiation Therapy


Seeking men with prostate cancer who will be getting radiation therapy. Suitable participants will go through 3 treatment cycles, each time getting either the active therapy or a placebo (fake therapy) in the form of 1 injection and then take 3 pills a day for 2 weeks. Afterwards they are followed for 5 years to see if the active treatment works better than the placebo.


In the same way as a vaccine protects us from infections, ProstAtak™ works using viruses that are changed so they don't cause harm the body. When injected into the tumor they make the body fight the tumor like an infection. The harmless virus also carries DNA and when it is given along with a medicine usually used to treat a different viral infection, it makes a chemical that kills the tumor cells. During the study you will be checked to see how you react to the treatments.

What we're hoping for

To find out if using a research treatment called ProstAtak™ along with standard radiation therapy for prostate cancer improves the long-term survival and quality of life for the patients.

Additional Information Identifier: NCT01436968

 Principal Investigator

Mitchell  Sokoloff, MD

UMass Memorial Health Care

 Study Contact

The Office  of Clinical Research



UMMS University Campus

55 Lake Ave North 

Worcester,MA 01655