Conquering Diseases

A Study Of Patients With Chronic Graft Versus Host Disease


Seeking adult men and women with chronic graft versus host disease for a study of Axatilimab at 3 different doses.


The purpose of this study is to compare how well axatilimab helps chronic graft versus host disease at different dose levels and to find out whether there are side effects from its use. Subjects will come in for infusions of the study drug on a varying calendar depending on their study assignment.

What we're hoping for

To determine how safe, effective, and well tolerated axatilimab may be in the treatment of chronic graft versus host disease compared to the usual treatment.

Additional Information Identifier: NCT04710576

 Principal Investigator

Muthalagu  Ramanathan, MD

UMass Memorial Health Care

 Study Contact

The Cancer  Research Office



UMMS University Campus

55 Lake Ave North 

Worcester,MA 01655