Conquering Diseases

Study Comparing Two Different Treatments For Rheumatoid Arthritis That Has Not Responded To Tnf-Biologic Treatment


Seeking men and women whose rheumatoid arthritis has not responded to TNF-biologic treatment for a study comparing two different types of treatments (non-TNFi-biologic and tsDMARDs).


Participants in this study will be assigned to receive either a type of non-TNFi biologic or tsDMARDs treatment. All treatments are standard treatments for RA. If after 4 months your RA doesn't improve you can either switch to another medication or continue with the first. There will be 6 study visits over a year.

What we're hoping for

We are studying whether there are any advantages to patients whose rheumatoid arthritis has not responded to TNFi-biologic treatment to switch to non-TNFi biologic versus tsDMARDs treatment.

Additional Information Identifier: NCT04692493

 Principal Investigator

Jonathan  Kay, MD

UMass Memorial Health

 Study Contact

The Office  of Clinical Research



UMMH Memorial Campus

281 Lincoln St. 

Worcester,MA 01605