Conquering Diseases

Study Of An Investigational Drug For Treatment-Resistant Depression


Seeking men and women whose depression has not been fully helped by other treatments, also known as treatment resistant depression for a study of an investigational drug that contains a man-made form of psilocybin (the active ingredient in psychedelic mushrooms known as "magic mushrooms" or "shrooms")


Participants in this study will be randomly assigned to get either a one-time dose of the investigational drug or a placebo (looks like the investigational drug but contains no medicine). Following a screening period of up to 10 weeks during which participants will be weaned from their antidepressants before the one-time dosing. Following dosing there will be a 6-week follow-up period with regular study visits.

What we're hoping for

We are studying whether a one-time dose of an investigational drug containing a man-made form of the naturally occurring chemical compound, psilocybin found in psychedelic mushrooms is safe and effective for treatment resistant depression

Additional Information Identifier: Not Available

 Principal Investigator

Anthony  Rothschild, MD

UMass Memorial Health

 Study Contact

Michelangela  Yusif



UMass Chan University Campus

55 Lake Ave North 

Worcester,MA 01655