Conquering Diseases

Study Of An Investigational Drug For Multiple Myeloma Which Can't Be Treated With Autologous Stem Cell Transplant

Description

Seeking adults with newly diagnosed Multiple Myeloma (NDMM) that can't be treated with autologous stem cell transplantation for a study of an investigational drug called Belantamab Mafodotin added to treatment with Lenalidomide and Dexamethasone.

Overview

Participants in this study will be randomized to get either a Belantamab Mafodotin infusion or Daratumumab injection added to Lenalidomide and Dexamethasone treatment. Treatment cycles for Belantamab Mafodotin are every 8 weeks initially then every 12 weeks. Treatment with Daratumumab are weekly for 2 months, then every two weeks for 4 months and then once every 4 weeks. Participants getting Belantamab Mafodotin will need to have an eye exam before each dose.

What we're hoping for

We are comparing the investigational drug Belantamab Mafodotin to Daratumumab when added to Lenalidomide and Dexamethasone treatment for Multiple Myeloma that can't be treated with autologous stem cell transplantation on long term survival.

Additional Information

ClinicalTrials.gov Identifier: NCT06679101

 Principal Investigator

Muthalagu  Ramanathan, MD

UMass Memorial Health

 Study Contact

The Cancer  Research Office

508-856-3216

Cancer.research@umassmed.edu

 Location

UMass Chan University Campus

55 Lake Ave North 

Worcester,MA 01655

508-856-8989