Seeking people aged 12 to 85 years old with GuillainBarré Syndrome who experience muscle weakness and who have not been treated with plasma exchange or IV immunoglobulin for a study of an investigational drug.
Seeking people aged 18 to 70 with systemic lupus erythematosus (SLE) that is being treated with nonbiologic therapies (such as an oral corticosteroid, antimalarial, and/or immunosuppressant) for a study of an investigational monoclonal antibody drug injection.
Seeking hospitalized patients at UMass Memorial Heath with Type 2 Diabetes for a study to improve support following hospital discharge.
Seeking adults aged 81-60 with relapsing multiple sclerosis for a study of an investigational drug given as a weekly injection.
Seeking adults who have tested positive for antiphospholipid antibodies in their blood or have been diagnosed with antiphospholipid syndrome for a registry to collect their health information over 10 years to better understand how to prevent, treat, and cure antiphospholipid antibody-associated health conditions.
Seeking adults healthy volunteers and people with skin conditions such as skin lupus (cutaneous lupus erythematosus, CLE), scarring hair loss (primary cicatricial alopecias, PCAs), blistering conditions (pemphigus and pemphigoid conditions), scarring/fibrosis (scleroderma/morphea), and cancer (cutaneous T and B cell lymphomas) for a study collecting skin samples.
We are collecting blood samples from healthy controls and Systemic Lupus Erythematosus (SLE) patient samples to learn more about potential molecules that are responsible for the development of Lupus.
Seeking adults with interstitial lung disease but not idiopathic pulmonary fibrosis (IPF) for a study to collect information and samples to better understand when and why interstitial lung disease might develop into progressive pulmonary fibrosis.
Seeking men and women with rheumatoid arthritis for a study of a smartphone app for muscle strength assessments to diagnose sarcopenia (loss of muscle mass and function).
Seeking adults aged 18-70 with Myasthenia Gravis with generalized muscle weakness for a study of the safety and effectiveness of an investigational cell therapy for muscle weakness developed using the participants own white blood cells .
Seeking adults with severe systemic lupus erythematosus (lupus), idiopathic inflammatory myopathy or systemic sclerosis for a study of an investigational cell therapy where your own cells are used to make the investigational drug which will then be infused back into participants.
Seeking adults with Moderate to Severe Systemic Lupus Erythematosus for a study of an investigational drug that has previously been approved for use in arthritis.
Seeking adults diagnosed with skin-limited lupus (cutaneous lupus erythematosus or CLE) for a study collecting blood and skin samples to better predict the risk of progression to systemic disease (systemic lupus erythematosus or SLE).
Seeking men and women with Systemic Lupus Erythematous(SLE) and Lupus Nephritis for a biorepository study to collect health information and biological samples to help researchers learn more about the disease and help design future studies.
Seeking men and women whose active systemic lupus erythematosus (SLE) is being treated with non-biologic therapy for a study of an investigational drug.
Seeking men and women whose rheumatoid arthritis has not responded to TNF-biologic treatment for a study comparing two different types of treatments (non-TNFi-biologic and tsDMARDs).
Seeking adults who have inflammatory arthritis and who are willing to provide data by answering questionnaires, giving a blood sample and donating leftover tissue samples for a study to help researchers better understand inflammatory arthritis.
Seeking men and women aged 18-60 years old with secondary progressive multiple sclerosis (MS) with no relapses (nrSPMS) for a study of an investigational drug
Seeking men and women aged 18 to 65 with relapsing multiple sclerosis who have either not started, or have discontinued treatment with a disease modifying therapy for a study of an investigational drug.
Seeking people who been diagnosed with Multiple Sclerosis (MS) or a similar immune disorder of the central nervous system or their immediate family members for a study to better understand what causes these diseases and perhaps improve treatment.
Newly diagnosed (within 6 months) people with Multiple Sclerosis (MS) sought for a trial comparing "first line" (traditional) with "second line" (aggressive) treatments in preventing disability. This is a pragmatic trial which means that even though participants will be randomly assigned a treatment group, they and their doctor can change their treatment if needed.
We are collecting data and biological samples from people with infectious or inflammatory conditions of the bowel such as celiac disease, colitis, and Inflammatory Bowel Disease (IBD) and from people who do not have bowel disease to get a better understanding of these diseases.
Seeking overweight men and women who receive care at UMass Memorial for their chronic disease (such as atrial fibrillation, hypertension, diabetes, COPD, rheumatoid arthritis, or congestive heart failure) for a study about using a mobile and wearable devices to monitor their health.
Seeking blood samples from healthy volunteers and volunteers who have various autoimmune diseases, like type 1 diabetes
We are studying how skin diseases occur in the skin, including how immune cells choose to initiate disease as well as what causes them to enter the skin.
Seeking men and women with or without an inflammatory skin disease ( such as cutaneous lupus erythematosus, dermatomyositis, atopic dermatitis, alopecia areata, scleroderma, eczema, psoriasis, vitilago, or drug hypersensitivity) for a study to learn more about skin diseases and their response to light.