Conquering Diseases

146 Studies found

Alcoholic Hepatitis

Alcoholic Hepatitis Network Observational Study

Seeking people who are either diagnosed with alcoholic hepatitis, or a healthy volunteer who drinks at least 3 drinks per day for a study collecting biological samples (blood, urine, and stool) and health information to better understand alcoholic hepatitis.

Healthy Volunteers Wanted.

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Gyongyi Szabo

ALS

Testing Nurown To Treat Als

This study will evaluate the effectivenes and safety of repeat administrations of injections of NurOwn as compared to Placebo given three times two months apart to participants with ALS. The study will consist of a pre-treatment period of up to 5 months, treatment period for 4 months and a follow up period of 3 months.

ALS

Anal Cancer

Anal Fistula

Laser Fistula Study

Seeking Men and Women 18-65 years old who have a fistula-in-ano that needs treatment.

Ankylosing Spondylitis

Aortic Aneurysm

Aortic Aneurysm Repair Using Endovascular Surgery and Custom Made Devices

Seeking men and women over the age of 18 who have been diagnosed with an aortic aneurysm (bulging of the vein that carries blood to your heart) that because of their anatomy can't be treated using an FDA-approved graft. This study would use endografts that are customized by the doctor to the anatomy of each patient to treat these complex aortic aneurysms.

Atrial Fibrillation

Atrial Fibrillation

Atrial Fibrillation

Autism Spectrum Disorder

Gender

Male/Female

Age

5-17 years

Compensation

Offered

Image of Jean Frazier

Autism Spectrum Disorder

Study Of Social Communication In Autism Spectrum Disorder

We are looking for adolescents aged 13 – 17, who either have Autism Spectrum Disorder (ASD) or do not have ASD to participate in a research study of how the body responds when talking and interacting with other people.

Healthy Volunteers Wanted.

Autoimmune Skin Disease

Gender

Male/Female

Age

6yrs-Adults

Compensation

Offered

Image of John Harris

Autoimmune Skin Disease

Biliary Tract Cancer

Bladder Cancer

Bone Marrow Transplant

Bone, Joint, and Muscle Diseases

Gender

Male

Age

4-17 years old

Compensation

Offered

Image of Brenda Wong

Bowel Cancer

Brain and Spinal Cord Diseases

Multi-Arm Optimization Of Stroke Thrombolysis (Most)

Seeking men and women who are within the first few hours of experiencing an ischemic stroke (caused by a blood clot blocking blood flow to the brain) for a study comparing medication combinations to reduce the impact of the stroke.

Brain and Spinal Cord Diseases

Brain Aneurysms

NANO Registry

Seeking Men and Women 18-90 years old who have a small ruptured or un-ruptured aneurysm in the head.

Brain Aneurysms

Brain Aneurysms

Brain Aneurysms

Gender

Male/Female

Age

18-80 years

Compensation

None

Image of David Rex

Brain Aneurysms

Brain Injury

Impact of Fever Prevention in Brain Injured Patients

Seeking patients who have suffered a brain injury like ischemic stroke, intracerebral hemorrhage or subarachnoid hemorrhage for a study of an investigational medical device to prevent fever while in the hospital

Breast Cancer

Mammography Screening Study (TMIST)

This study is comparing two types of screening mammograms, Digital Mammograms and Tomosynthesis Mammograms, to see which is better for breast cancer screening.

Breast Cancer

Breast Cancer

Breathing Study

Cancer Genetics

Cancer Genetics

A Study of Cancer Tumors (AVATAR)

This study is collecting tumor tissue, body fluids and blood samples from patients undergoing biopsies or surgery to gain a better understanding of different cancers.

Cancer Research

Study Of An Investigational Drug For Advanced Cancer

This study will evaluate the safety and effectiveness of an investigational drug for multiple types of advanced cancer that haven't responded to treatment and have spread to other parts of the body (metastatic).

Cancer Research

Cancer Research

Cancer Research

Chronic Pancreatitis

Chronic Pancreatitis

Clostridium Difficile

Clostridium Difficile

Cystic Fibrosis

Gender

Male/Female

Age

12 years+

Compensation

Offered

Image of Ted Kremer

Cystic Fibrosis

Gender

Male/Female

Age

All

Compensation

None

Image of Ted Kremer

Cystic Fibrosis

Gender

Male/Female

Age

18 years+

Compensation

Offered

Image of David Fish

Cytomegalovirus (CMV)

Gender

Male/Female

Age

12 and older

Compensation

Offered

Image of Laura Gibson

Cytomegalovirus (CMV)

Gender

Male/Female

Age

16 yrs & older

Compensation

Offered

Image of Laura Gibson

Cytomegalovirus (CMV)

Gender

Male/Female

Age

Child

Compensation

Offered

Image of Laura Gibson

Degenerative Spine Disease

LimiFlex Control Site Study

Seeking adults with degenerative spondylolisthesis with lumbar spinal stenosis whose doctors have recommended back surgery to address the pressure on your spinal cord or spinal nerves

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Michael Stauff

Digestive and Liver Diseases

Digestive and Liver Diseases

Gender

Male/Female

Age

All

Compensation

None

Image of Krunal Patel

Digestive and Liver Diseases

Gender

Male/Female

Age

Adult

Compensation

None

Image of David Cave

Digestive and Liver Diseases

Duchenne Muscular Dystrophy

Germ Cell Cancer

Gynecological Cancer

Head and Neck Cancer

Study for Head and Neck Cancer

This study is looking at different chemotherapy combinations along with radiation for the treatment for locally advanced head and neck squamous cell carcinoma.

Heart and Blood Vessel Diseases

Heart Artery Blockage

Heart Attack

Gender

Male/Female

Age

Adult

Compensation

None

Image of Craig Smith

Heart Failure

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Chad Darling

Heart Failure

Heart Failure

Hepatitis C Infection

Gender

Male/Female

Age

18+

Compensation

Offered

Image of Gyongyi Szabo

Hormonal Diseases and Diabetes

Gender

Male/Female

Age

18 and over

Compensation

None

Image of Dale Greiner

Hormonal Diseases and Diabetes

Infectious Diseases

Study Of How The Flu Affects Blood Cells

Seeking healthy adults and adults who have been suffering influenza-like illness for no more than 14 days for a study of how the flu or flu-like infections affect their blood cells.

Healthy Volunteers Wanted.

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Robert Finberg

Inflammation of Esophagus

Gender

Male/Female

Age

12 and older

Compensation

Offered

Image of David Cave

Inflammatory Bowel Disease

Inflammatory Bowel Disease

Inflammatory Bowel Disease

Inflammatory Bowel Disease

Inflammatory Bowel Disease

Inflammatory Bowel Disease

Inflammatory Bowel Disease

Inflammatory Bowel Disease

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of David Cave

Inflammatory Bowel Disease

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of David Cave

Inflammatory Bowel Disease

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of David Cave

Inflammatory Bowel Disease

Gender

Male/Female

Age

Adult

Compensation

None

Image of David Cave

Inflammatory Bowel Disease

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of David Cave

Kidney Cancer

Study of Kidney Tumors in Younger Patients

Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.

Kidney Cancer

Leukemia (ALL)

Leukemia (ALL)

Leukemia (AML)

Liver Cancer

Liver Cirrhosis

Investigational Study For Patients With Liver Cirrhosis (Cobalt)

The study drug, Ocaliva (OCA), already has FDA approval but we need to gather more data about how well it works on patients with Primary Biliary Cholangitis (PBC) when given along with the usual care for this condition. Half of the study participants will get the study drug and half will get a placebo (fake pill). You cannot choose or know which pill group you belong to.

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Gyongyi Szabo

Lung Cancer

Lung Cancer

Lung Cancer

Lung Cancer

Lung Cancer

Lung Cancer

Lung Cancer

Lung Cancer

Lung Cancer

Lung Diseases and Breathing

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Jens Walz

Lung Diseases and Breathing

Gender

Male/Female

Age

Adult

Compensation

None

Image of Jens Walz

Lung Diseases and Breathing

Macular Degeneration

Macular Degeneration and Other Related Ocular Disorders

Children and adults who either have macular degeneration or are closely related to someone who has macular degeneration are sought for a study of macular degeneration and other related ocular disorders to prevent visual loss and blindness for current and future generations

Healthy Volunteers Wanted.

Gender

Male/Female

Age

7 and older

Compensation

None

Image of Johanna Seddon

Metastatic Cancer

Mindfulness Study

Mindfulness Heart Study

Seeking men & women 18 years old and over who have a cardiomyopathy (impairment of your heart muscle strength) from coronary artery disease (hardening of the arteries).

Multiple Sclerosis

Multiple Sclerosis

Multiple Sclerosis

Traditional Versus Early Therapy for Multiple Sclerosis (TREAT-MS) Trial

Newly diagnosed (within 6 months) people with Multiple Sclerosis (MS) sought for a trial comparing "first line" (traditional) with "second line" (aggressive) treatments in preventing disability. This is a pragmatic trial which means that even though participants will be randomly assigned a treatment group, they and their doctor can change their treatment if needed.

Multiple Sclerosis

Multiple Sclerosis

Myelodysplastic Syndromes

The National Myelodysplastic Syndromes (MDS) Study

This study is looking to enroll patients who have recently been diagnosed with one of the blood disorders included among Myelodysplastic Syndromes (MDS) to better understand the natural history of the disease.

Neuroblastoma

Neuroblastoma

Neuroblastoma

Nonalcoholic Steatohepatitis

Regenerate: An Investigational Study Drug Designed To Help Patients With Nonalcoholic Steatohepatitis (Nash)

Nonalcoholic Steatohepatitis (NASH) is a disease that results when fat accumulates in the liver and eventually causes inflammation and scarring called fibrosis. Ocaliva (OCA) is an FDA approved drug for treating another type of liver disease. The purpose of this study is to test whether an experimental drug, OCA, is safe and effective in treating advanced scarring of the liver due to NASH.

Gender

Male/Female

Age

18+

Compensation

Offered

Image of Gyongyi Szabo

Nonalcoholic Steatohepatitis

Aurora: A Study Of An Experimental Drug For Liver Scarring Caused By Nash

Nonalcoholic Steatohepatitis (NASH) is a disease that results when fat accumulates in the liver and eventually causes inflammation and scarring called fibrosis. The purpose of this study is to test whether an experimental drug, CVC, is safe and effective in treating advanced scarring of the liver due to NASH.

Gender

Male/Female

Age

18+

Compensation

Offered

Image of Gyongyi Szabo

Nonalcoholic Steatohepatitis

Gender

Male/Female

Age

18-75 years

Compensation

Offered

Image of Gyongyi Szabo

Nonalcoholic Steatohepatitis

Reverse: A Study Of An Investigational Drug For Compensated Cirrhosis Due To Nonalcoholic Steatohepatitis (Nash)

Nonalcoholic Steatohepatitis (NASH) results when fat accumulates in the liver and causes inflammation and scarring called fibrosis. Fibrosis can lead to cirrhosis which impairs liver function. Ocaliva (OCA) is an FDA approved drug for treating another type of liver disease. This study will test if Ocaliva (OCA) is safe and effective in treating cirrhosis of the liver caused by advanced NASH.

Gender

Male/Female

Age

18 or older

Compensation

Offered

Image of Gyongyi Szabo

Opioid Overdose

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of Kavita Babu

Pancreatic Cancer

Pancreatic Cancer

Study to Develop Pancreatic Cancer Blood Test

This study is collecting information from patients who are at a high risk of developing pancreatic cancer based on family history or genetic mutations to see if a pancreatic cancer screening blood test can be developed.

Peripheral Artery Disease

Peripheral Artery Disease

Prostate Cancer

Experimental Treatment for Metastatic Prostate Cancer

This study is looking at an experimental treatment for prostate cancer that has spread to other parts of the body and has grown even though treatments to lower the amount of male sex hormones are being used to manage the cancer.

Prostate Cancer

Pyruvate Kinase

Rectal Cancer

Rectal Cancer

Rectal Cancer Surgery Research

Seeking adults with rectal cancer requiring surgery for a study comparing an investigational surgery to the standard surgery technique

Reproductive and Women Health

Study To Develop A Screening Test For Preeclampsia In Pregnant Women

Pregnant women who are in their late 2nd to 3rd trimester who have high blood pressure are sought for a study to develop a screening test for preeclampsia in pregnant women. We will collect samples of your blood, urine, and saliva to see if we can detect levels of a protein that would help accurately predict who will get preeclampsia.

Reproductive and Women Health

Study Of The Effects Of High Blood Pressure During Pregnancy

Pregnant women with either normal or high blood pressure sought for a study of the effects of high blood pressure during pregnancy. The study will assess whether future cardiovascular disease or serious pregnancy complications like preeclampsia can be better detected & prevented.

Healthy Volunteers Wanted.

Rhabdomyosarcoma

Rheumatoid Arthritis

Rheumatoid Arthritis

Gender

Male/Female

Age

18 or older

Compensation

Offered

Image of Jonathan Kay

Schizophrenia

Telmisartan Pilot Study

Seeking Men and Women 18-65 yeras old who have been diagnosed with schizophrenia or schizoaffective disorder who has not experienced a significant relief of symptoms in spite of being treated with one or more approved medicines for the treatment of their illness.

Gender

Male/Female

Age

18-65 years

Compensation

Offered

Image of Xiaoduo Fan

Schizophrenia

Skin and Hair Diseases

Stem Cell Transplant

Stem Cell Transplant

Stroke

Experimental Treatment for Strokes

This study is looking at an experimental treatment for patients diagnosed with a stroke caused by a blockage in the blood vessels within the brain.

Stroke

Stroke

Study of Drug Therapy to Prevent Stroke from Happening Again

Seeking Ischemic (caused by reduced blood flow by narrowed or blocked arteries) stroke survivors aged 45 and older for a study of an investigational therapy using anticoagulant drugs (aspirin or apixiaban) for the prevention of another stroke

Suicide Risk

Surgery

Gender

Male/Female

Age

Adult

Compensation

None

Image of Jens Walz

Surgery

Gender

Male/Female

Age

Adult

Compensation

Offered

Image of John Kelly

Tissue Injury

Portable Hyperspectral Imaging (HSI) Study

Seeking Men and Women 18 years or older patients who are having an operation that will require the creation of a flap of tissue (where a piece of skin/muscle is taken from one part of the body and moved to another part), or because you have a traumatic degloving injury (an injury where the skin is torn away from the tissue underneath).

Type 1 Diabetes Mellitus

Uterine Study

Vitiligo

Vitiligo

Gender

Male/Female

Age

7-85 years old

Compensation

None

Image of John Harris

Vitiligo