Seeking men and women to help assess how well a specific drug called INT-787 works in participants with severe alcohol-associated hepatitis (sAH).
Seeking men and women, 18 years or older who are currently receiving services for substance use disorder and who have co-occurring mental health disorders
Seeking adults aged 81-60 with relapsing multiple sclerosis for a study of an investigational drug given as a weekly injection.
Seeking adults healthy volunteers and people with skin conditions such as skin lupus (cutaneous lupus erythematosus, CLE), scarring hair loss (primary cicatricial alopecias, PCAs), blistering conditions (pemphigus and pemphigoid conditions), scarring/fibrosis (scleroderma/morphea), and cancer (cutaneous T and B cell lymphomas) for a study collecting skin samples.
Seeking adults with Moderate to Severe Systemic Lupus Erythematosus for a study of an investigational drug that has previously been approved for use in arthritis.
Seeking adults diagnosed with skin-limited lupus (cutaneous lupus erythematosus or CLE) for a study collecting blood and skin samples to better predict the risk of progression to systemic disease (systemic lupus erythematosus or SLE).
Seeking men and women whose Systemic lupus erythematosus (SLE) is causing damage to their kidneys (refractory lupus nephritis) for a study of an investigational cell therapy
Seeking men and women with Systemic Lupus Erythematous(SLE) and Lupus Nephritis for a biorepository study to collect health information and biological samples to help researchers learn more about the disease and help design future studies.
Seeking men & women over 18 years old who have a blood disorder or malignancy to investigate normal and abnormal cell growth.
Men and women over 16 years old undergoing transplantation with unlicensed CBUs (cord blood units) will be enrolled. Cord blood units not meeting FDA requirements or not yet approved by the FDA may be used for transplant if the transplant is done as part of a study.
Adult male and female U.S. recipients of allogeneic or autologous HSC transplants or cellular therapies are eligible to participate in the NMDP Research Sample Repository.
Seeking people diagnosed with Chronic Fatigue Syndrome, Long COVID, Chronic Lyme, Fibromyalgia, Gulf-War Illness, Hypermobile EDS or Hypermobility Syndrome, Postural orthostatic tachycardia syndrome (POTS),or Orthostatic Intolerance for a study collecting blood, urine, saliva and skin tissue.
Seeking adults aged 18 and older who either have Facioscapulohumeral Muscular Dystrophy (FSHD) or are healthy volunteers for a study to identify genetic biomarkers for the disease and better understand what causes it, and why symptoms vary widely among people who have it.
Seeking men and women whose doctor has recommended surgery to relieve pain resulting from damage to a disc in their back being pushed out of place (herniated) for a study of an investigational device to prevent the disc from reherniating.
Seeking adults with degenerative spondylolisthesis with lumbar spinal stenosis whose doctors have recommended back surgery to address the pressure on your spinal cord or spinal nerves
Seeking boys aged 2 and older with Duchenne Muscular Dystrophy who have been prescribed Vamorolone (Agamree) for a study of the long-term safety of the drug.
Seeking adults who have had low back pain for at least 3 months for a study of whether things such as activity levels, sleep, heart rate, or emotions impact how their pain responds to mindfulness treatment.
Seeking boys aged 6-14 years old who have previously been treated with adeno-associated virus (AAV) based gene therapy for a study of an investigational drug
Seeking men and women with Psoriatic Arthritis which has not responded to an initial type of treatment for a study comparing whether switching to a different type of treatment is the same, better, or worse.
Seeking boys aged 4 to 16 for a study of an investigational drug to increase dystrophin protein levels in muscles.
Seeking men and women whose active systemic lupus erythematosus (SLE) is being treated with non-biologic therapy for a study of an investigational drug.
Seeking men and women whose rheumatoid arthritis has not responded to TNF-biologic treatment for a study comparing two different types of treatments (non-TNFi-biologic and tsDMARDs).
Seeking boys and men with Duchenne muscular dystrophy (DMD) or Becker Muscular Dystrophy (BMD) to provide samples including blood, plasma, serum, urine, as well as the remainders of tissue samples collected as part of their usual clinical care for a biorepository.
Seeking male participants aged 10-21 years of age who have been diagnosed with Duchenne Muscular Dystrophy (DMD) for participation in an imaging study.
Seeking men and women whose broken arms or legs will need to be treated with surgery for a study of what treatment practices best prevent infection.
Seeking adults who have inflammatory arthritis and who are willing to provide data by answering questionnaires, giving a blood sample and donating leftover tissue samples for a study to help researchers better understand inflammatory arthritis.
This study is intended to collect data from medical records on patients who have Duchenne Muscular Dystrophy
Seeking men and women aged 18-60 years old with secondary progressive multiple sclerosis (MS) with no relapses (nrSPMS) for a study of an investigational drug
Seeking people aged 65 and older for a study of a digital screening tool for mild cognitive impairment using audio recordings.
Seeking people aged 12 and older with epilepsy who likely have primary generalized tonic-clonic seizure (PGTCS) for a study of an investigational drug.
Seeking men and women with multiple system atrophy and experience dizziness or feeling faint due to neurogenic orthostatic hypotension for a study of an investigational drug.
Seeking men and women aged 18 and older for a study of a device to help develop a Magnetic resonance imaging (MRI) technique to improve scans of the brain.
Seeking men and women over the age of 65 for a study of an investigational device to screen for cognitive impairment.
Seeking women and men who have started ocrelizumab treatment for their Multiple Sclerosis (MS) within the past month or people whose MS is being being treated with therapies other than ocrelizumab for a study looking at the incidence of cancer in the future.
This is a registry to collect medical record information from people living with Multiple Sclerosis (MS) to better understand the disease and develop new treatments
Seeking men and women who have been referred for minimally invasive endovascular treatment for aneurysm, stroke or arterio-venous malformations at the UMass Memorial Neurointerventional Radiology (NIR) angiosuite for a study comparing different imaging techniques.
Seeking patients of the UMass Memorial Epilepsy Monitoring Unit aged 18 and older for a study of an investigational device to detect and predict epileptic seizures.
Seeking men and women aged 18 to 65 with relapsing multiple sclerosis who have either not started, or have discontinued treatment with a disease modifying therapy for a study of an investigational drug.
Seeking people aged 18-75 with Non-Active Secondary Progressive Multiple Sclerosis for a study of an investigational drug given as a nasal spray.
Seeking men and women with dystonia and essential tremor undergoing deep brain stimulation (DBS) for a study to better understand laryngeal dystonia (LD) and voice tremor (VT), which are neurological conditions causing abnormal voice and speech control.
Seeking men and women diagnosed with Multiple sclerosis (MS) within the past 2 years for a study of whether ocrelizumab (study drug) can be used for a period of time rather than permanently and still control your early relapsing MS disease activity.
Seeking men and women who have had a recent stroke or transient ischemic attach (TIA) often called a "mini-stroke" for a study of the benefits of using a continuous positive airway pressure (CPAP) machine while sleeping.
Seeking men and women with atrial fibrillation and a recent brain hemorrhage causing increased risk for stroke for a study of blood thinners to reduce risk of stroke.
Seeking men and women with multiple sclerosis (MS) that hasn't responded to previous treatment for a study of an experimental drug.
Seeking men and women whose doctor has recommended treatment for an acute ischemic stroke for a study collecting blood clots and medical information to better understand how to treat and prevent acute ischemic stroke.
Seeking men and women aged 50 and older who have had bleeding in the brain (brain hemorrhage) for a study comparing continuing or stopping statin drug use treatment on the risk of having another brain hemorrhage.
Seeking people who been diagnosed with Multiple Sclerosis (MS) or a similar immune disorder of the central nervous system or their immediate family members for a study to better understand what causes these diseases and perhaps improve treatment.
Seeking men and women with multiple sclerosis for a study of how common sleep apnea is and whether sleep apnea affects MS symptoms.
Seeking men and women with Amyotrophic Lateral Sclerosis (ALS) to participate in a research trial to test several different investigational treatments.
Seeking men and women whose multiple sclerosis has remained active despite treatment for a study comparing blood stem cell transplantation to other available treatments for multiple sclerosis.
Seeking men and women aged 18 and older who have been admitted to the hospital intensive care unit following a traumatic brain injury for a study of how care received in the hospital impacts long-term recovery.
Seeking men and women with relapsing multiple sclerosis whose doctors has decided to start treatment with clabridine tablets because other pills were not working well.
This study is enrolling men and women who have had a traumatic brain injury in order to compare outcomes when medical care is delivered based on either monitoring the pressure in the brain or monitoring both the pressure in the brain and the amount of oxygen in the brain.
Newly diagnosed (within 6 months) people with Multiple Sclerosis (MS) sought for a trial comparing "first line" (traditional) with "second line" (aggressive) treatments in preventing disability. This is a pragmatic trial which means that even though participants will be randomly assigned a treatment group, they and their doctor can change their treatment if needed.
Seeking adults with metastatic or Cholangiocarcinoma that can't be removed through surgery and hasn't responded to therapy for a study of an investigational drug for bile duct cancer.
Seeking adult cancer survivors for a study of a physical activity program
Seeking men, women, and children to participate in a trial looking at a combination of drugs for use in treating a type of cancer called rhabdomyosarcoma (RMS).
Seeking people aged 5-60 newly diagnosed with early (Stage I or II) Hodgkin lymphoma that has not yet been treated for a study comparing the effect of adding immunotherapy to the standard chemotherapy to the standard chemotherapy alone.
Seeking UMass Memorial patients who are current or former smokers for a study about lung cancer screening
Seeking people with Mycosis Fungoides for a study to develop a test for Mycosis Fungoides.
Seeking women scheduled for a routine screening mammogram for a study comparing Artificial Intelligence (AI) software to standard guidelines for predicting breast cancer risk.
Seeking men and women who have been referred for follow-up imaging after a positive CT scan screen for lung cancer for a study of a blood test for early detection of lung cancer.
Seeking people aged up to 21 years for a study of decreasing the length of chemotherapy treatment for people with low risk rhabdomyosarcoma and increasing the length of chemotherapy treatment for people with high risk rhabrhabdomyosarcoma.
Seeking men and women with metastatic cancer that has spread to their brain and progressed or grew back after treatment for a study of an investigational immunotherapy drug based on the gene type and source of the original cancer to prevent growth of metastatic tumors in the brain.
Seeking men and women whose meningioma (cancer of the brain covering) has gotten bigger or grew back after treatment for a study of whether cancer drugs targeting tumors based on their genetics is better, the same, or worse than the standard treatment for meningiomas.
Seeking male and female participants under the age of 25, who were diagnosed with Chronic Myeloid Leukemia before the age of 18, to determine if they can stop taking their TKI medication and remain in remission as well as if restarting TKI will re-achieve remission.
Seeking people aged 2-21 years who have been diagnosed with Philadelphia chromosome positive (Ph+) or ABL-class fusion positive Acute Lymphoblastic Leukemia (ALL) for a study of whether using a less toxic chemotherapy in combination with a drug called imatinib can keep the cancer from returning after treatment.
Seeking men and women who have had a lung nodule detected during imaging for collection of nasal swab and blood samples.
Seeking people aged 30 and younger newly diagnosed with diffuse anaplastic Wilms tumor, a type of cancer that occurs in the kidney, for a study of experimental treatment regimen because no standard treatment regimen currently exists.
Seeking men and women who are current smokers for a study of motivational text messages to help people stop smoking.
Seeking children and young adults 31 years old or younger who have been newly diagnosed with standard risk B-cell Acute Lymphoblastic Leukemia (B-ALL), Down syndrome B ALL or localized B-cell Lymphoblastic Lymphoma (B-LLy) for a study of chemotherapy.
Children and young adults up to age 25 with High-Risk B-cell acute lymphoblastic leukemia (B-ALL) sought for a study of an investigational drug in combination of chemotherapy based on individual disease characteristics to improve 5-year disease-free survival (DFS).
Seeking children and young adults whose CD22+ B-Acute Lymphoblastic Leukemia (B ALL) has come back (relapsed) after treatment or has not responded (refractory) for a study of an investigational drug. While the investigational drug has been approved for use adults with leukemia, it has not yet been approved for use in children.
We are studying how well active surveillance, or two different combinations of chemotherapy work in treating children 11 and older and adults under age 25 with germ cell tumors.
Seeking Male & Female patients age 0-30 years who have a kidney tumor (an abnormal growth of cells or tissues in the kidney that may be benign or malignant) or a tumor outside the kidney called a malignant rhabdoid tumor or an extrarenal Wilms tumor.
Seeking Male and Female age 0-25 years who may have cancer or another condition that is characterized by abnormal cell growth but may be benign (not cancer), or may already have been diagnosed with cancer.
Seeking male & female patients who have been diagnosed with rhabdomyosarcoma (cancer that forms in the soft tissues, such as muscle).
Seeking men and women newly diagnosed with cancer for a study using artificial intelligence to create a more easily understood treatment plan summary.
Seeking men and women undergoing blood or bone marrow transplants, cord blood transplants or other cell therapy work for a collection of blood samples for future research
Seeking people with early-stage endometrial cancer for a study comparing radiation therapy and surgery to surgery alone for early-stage endometrial cancer treatment.
Seeking women with newly diagnosed early stage (I or II) uterine leiomyosarcoma for a study of whether taking an investigational drug following surgery is better than not taking the drug at preventing the cancer from returning.
Seeking adults with locally advanced non-small cell lung cancer for a study of adding radiation therapy to standard treatment for non-small cell lung cancer that cannot be treated by surgery (inoperable).
Seeking adults with Acute Myeloid Leukemia with an NPM1 mutation or KMT2A rearrangement for a study of an investigational drug to be used in combination with other chemotherapy drugs.
Seeking adults with early stage triple negative breast cancer for a study comparing a shorter chemo-immunotherapy to the usual therapy.
Seeking people with small cell lung cancer that has spread to other parts of the body (metastatic) for a study of whether adding radiation therapy to the usual treatment is better, worse or the same as the usual treatment alone following chemo-immunotherapy.
Seeking women whose endometrial cancer has previously been treated with platinum-based chemotherapy and immunotherapy for a study of an investigational drug.
Seeking men and women with a specific form of lung cancer to test if a combination of two specific drugs is beneficial.
Seeking men and women whose high-risk, non-muscle invasive bladder cancer has not spread to the muscle for a study comparing the standard Bacillus Calmette-Guerin (BCG) immunotherapy to an investigational chemotherapy drug combination.
Seeking adults whose triple-negative breast cancer remained following surgery and pre-surgery treatment for a study of an investigational drug.
Seeking men and women with colorectal cancer who will undergo colorectal surgery to remove part of their colon or rectum for a study of the healing process
Seeking men and women with advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes for a study comparing targeted drug combinations
Seeking people with locally advanced or metastatic platinum-resistant ovarian, endometrial, or urothelial cancer for a study of an investigational drug.
Seeking people who have who have already taken endocrine therapy for two to five years for their early-stage ER+/HER2- breast cancer and have a higher-than-average risk for their cancer to return for a study to compare the investigational drug to standard hormone therapy.
Seeking men and women who have a type of cancer that affects the B-cells (a type of white blood cells) in your blood that has not responded to, or who could not tolerate, the standard treatments normally given for this type of cancer for a study of an investigational drug.
IRONMAN Registry aims to collect detailed information about the participants in the study at the time of enrollment and to follow their medical care to better understand what treatments work and where there are unmet needs in their treatment.
Seeking men and women aged 18-65 years whose large B-Cell lymphoma has not responded or come back after treatment for a study of an investigational drug combination.
Seeking men and women aged 18 and older who have upper tract urothelial cancer for a study of whether adding an immunotherapy drug to the standard chemotherapy aid in preventing or delaying the cancer from growing.
Seeking men and women whose non-small cell lung cancer (NSCLC) has spread outside the lungs, and has a change in the gene called EGFR (epidermal growth factor receptor) and has not yet been treated for a study of an investigational drug combination.
Seeking men and women at risk for pancreatic cancer due to family or personal history willing to participate in an detection and prevention study.
Seeing men and women whose renal cell cancer has spread to their bones for a study of an investigational drug combination to reduce pain.
Seeking men and women with cancer of the esophagus or gastric junction for a study of whether a blood sample analyzed to find evidence of a cancer tumor (liquid biopsy) might be a useful tool to predict how well the cancer has responded to treatment.
Seeking adults with non-small cell lung cancer for a study comparing immunotherapy to targeted therapy based on tumor characteristics
Volunteers with advanced prostate cancer that has spread to their bones sought for a study of an investigational drug to assess if it stops the cancer from growing
Seeking infants aged 6-8 months who have an older sibling with autism for a study to determine if intensive early intervention before at 15 months improves communication and language skills at 24 months.
Seeking children aged 2.5 to 7 years old suspected to have Autism Spectrum Disorder (ASD) and those who do not for a study of a test to diagnose and assess ASD.
Seeking men aged 18-45 with Fragile X Syndrome for a study of an investigational drug.
Seeking infants admitted to the NICU with an unexplained likely genomic illness for a study of the benefit of genomic testing on their care.
Seeking teens aged 15-18 years old who were enrolled in the ELGAN study of premature infants between April 2002 and August 2004 for a follow-up study of health and developmental progress.
Seeking adults with inflammatory bowel disease to participate in a registry to better understand the disease, predict disease flare and improve treatment.
Seeking men and women with an anal fistula that does not require extensive surgical repair for a study of an investigational treatment
Seeking people whose recurrent Clostridium difficile (C. diff) infection has not responded to standard antibiotic treatments for a study to see if fecal microbiota transplantation is effective for treating C. diff infection.
We are collecting data and biological samples from people with infectious or inflammatory conditions of the bowel such as celiac disease, colitis, and Inflammatory Bowel Disease (IBD) and from people who do not have bowel disease to get a better understanding of these diseases.
Seeking men and women with liver disease who are seen at the UMass Memorial hepatology clinic for a food and nutrition survey.
Seeking children aged 2-17 with moderately to severely active ulcerative colitis that has not responded to treatment for a study of an investigational drug to prevent inflammation.
Seeking men and women aged 18-75 with moderately to severely active Crohn's Disease (CD) that has not responded to treatment for a study of an investigational drug.
Seeking men and women over 18 years of age who are having a specific kind of endoscopic procedure with imaging to determine how well a a computer program can analyize these images compared to what your doctor determines.
Seeking men and women with uncomplicated diverticulitis for a study of fecal transplantation as an alternative to surgery to treat diverticulitis.
Seeking men and women aged 65 and older for a study of changes in the microbiome in the intestines of seniors when they move into a long-term care facility.
Seeking men and women aged 50 and older who will be transferred to a long-term care facility, have been a resident of a long-term care facility for more than one month, or who live in the community and attend senior center programs for a study of the gut microbiome to better understand risk factors for Clostridium Difficile (an intestinal infection that causes severe diarrhea)
Seeking people with eyelid motility disorder preventing their eyelids from opening and closing normally for a study of an investigational device.
Children and adults who either have macular degeneration or are closely related to someone who has macular degeneration are sought for a study of macular degeneration and other related ocular disorders to prevent visual loss and blindness for current and future generations
Seeking adult male and female healthy volunteers for a national research program enrolling one million people across the U.S. to help build one of the most diverse health databases in history.
Seeking male participants aged 12 to less than 18 years of age for a study of an investigational drug and it's safe and effectiveness for participants with Fragile X Syndrome
Seeking boys and girls with Fragile X Syndrome who were born between 2003 and 2017 for a registry to better understand how to manage and treat Fragile X Syndrome.
Seeking people aged 18 and older to test ways to make materials for an upcoming study more easily understood
Seeking men and women who get their care at UMass Memorial for a chronic health condition such as heart disease, diabetes or kidney disease for a study of an investigational device embedded in a toilet seat to remotely monitor cardiac health.
Seeking men and women 18 years and older who have been referred for a procedure called a Coronary angiography to look at blockages in the coronary arteries
Seeking men and women who are experiencing symptoms of a heart attack including chest pain and shortness of breath for a study of the effect of stress on heart function and the development of stress cardiomyopathy.
Stroke survivors aged 50 and over sought for a study to develop and test a wearable sensor to monitor for atrial fibrillation (abnormal heartbeats)
Seeking women who get their OB care at UMass Memorial and are 8-26 weeks pregnancy and have chronic hypertension or gestational hypertension for a study to improve blood pressure management in pregnancy.
Seeking men and women admitted to UMass Memorial for heart failure for a study of an investigational device worn as a vest that may be able to detect a buildup of fluid in the lungs to provide an early diagnosis of heart failure.
Seeking adults with heart failure with mildly reduced or preserved ejection fraction for a study of a surgically implanted investigational device.
Seeking men and women aged 22-85 with atrial fibrillation who have a low to moderate risk for stroke for a study comparing continuous treatment with anticoagulants to 30 days of anticoagulant treatment followed by monitoring for atrial fibrillation using a smartwatch
Seeking African-American or other black men and women with atrial fibrillation or flutter that is not being treated with an anticoagulant or blood thinner for a storytelling intervention.
Seeking men and women with Chronic Limb Threatening Ischemia (CLTI) who have been referred for surgical treatment of their Below-the-Knee (BTK) Atherosclerotic Disease for a study of an investigational device
Seeking men and women 18 years of age or older who have been diagnosed with a specific type brain aneurysm for study of the long term safety of an approved device (WEB®) intended to treat this issue.
Seeking men and women 18 to 80 years of age who have been diagnosed with a specific type brain aneurysm for study of an investigational device intended to treat this issue.
Seeking men and women with heart failure due to a dilated left ventricle (heart chamber that pumps blood) for a study of an investigational device.
Seeking men and women with a blood clot causing Deep Vein Thrombosis for which their doctor has recommended surgical treatment for a study of an investigational device inserted into the vein using a catheter to remove the clot.
Seeking men and women with peripheral artery disease (PAD) causing pain in the legs when walking or climbing stairs for a study of an investigational dietary supplement combination to improve blood flow.
Volunteers who are at risk for having heart disease, taking aspirin, and will be or have already undergone a cardiac catheterization sought for a study of how the body makes blood clots and its effect on the risk for heart attack and stroke.
Seeking men & women 18 years old and over who have a cardiomyopathy (impairment of your heart muscle strength) from coronary artery disease (hardening of the arteries).
Seeking men and women over the age of 18 who have been diagnosed with an aortic aneurysm (bulging of the vein that carries blood to your heart) that because of their anatomy can't be treated using an FDA-approved graft. This study would use endografts that are customized by the doctor to the anatomy of each patient to treat these complex aortic aneurysms.
Seeking men and women who have been treated for episodes of low blood sugar at the UMass Memorial Diabetes Center of Excellence for a study to see if a smartwatch can sense low blood sugar.
Seeking Latinx men and women with type 2 diabetes for a study to develop and test a program to help with diabetes self-management.
Seeking men and women with type 2 Diabetes Mellitus to participate in an expert panel for a study to develop and test a technology to help people manage their diabetes.
Seeking blood samples from healthy volunteers and volunteers who have various autoimmune diseases, like type 1 diabetes
Seeking healthy people who may have been previously infected with influenza A virus (IAV), coronaviruses such as Covid, Epstein-Barr virus (EBV, the virus that causes mononucleosis or “mono”), cytomegalovirus (CMV) or the virus that causes roseola to collect blood, saliva, and nasal swabs to study immune system responses to the virus.
We invite people who are Latinx and/or Black and have been vaccinated against COVID-19 to tell us how COVID-19 has affected you and your family and your experience with getting the COVID-19 Vaccines and the first booster.
Seeking parents of kids aged 5-17 who receive their care at UMass Memorial for a research survey about their intentions on having their child vaccinated against COVID-19.
Seeking men and women aged 65 and older who have been hospitalized for what may be pneumonia for a study of the effectiveness of vaccines against pnuemonia.
Seeking men and women aged 18 and older who get their care at UMass Memorial clinics to participate in a focus group on outreach materials for COVID-19 vaccination.
Seeking children who have been diagnosed with influenza in the past 7 days and healthy children willing to donate a blood sample for a study of how influenza affects blood cells of children.
Seeking men and women who come to the emergency room because of a cough or difficulty breathing for a study collecting blood and nasal swabs to study respiratory illness.
Seeking men and women with sleep problems (excessive drowsiness, problems falling and staying asleep, and problems with sleep-wake patterns) that started or got worse for at least 12 weeks following a COVID-19 infection for a study of treatments for sleep problems.
Seeking hospitalized men and women who are on supplemental oxygen because of a viral lung infection for a study of an investigational drug added to the usual treatment
Seeking men and women who have had stem cell transplant or cellular therapy for their blood cancer for a study of a COVID-19 vaccine.
Seeking people aged 21 and younger who have lyme disease and likely have meningitis that has not yet been treated. To participate in a study comparing two different antibiotic treatments
Seeking healthy adults and adults who have been suffering influenza-like illness for no more than 14 days for a study of how the flu or flu-like infections affect their blood cells.
Seeking people who are in need or may soon be in need of dialysis treatment through an Arteriovenus Fistula (AVF) for a study of the long-term safety of a device approved by the FDA and used to create the AVF.
Seeking men and women with Chronic Obstructive Pulmonary Disease (COPD) for a study of an mobile digital device app to provide in-home support to manage COPD.
Seeking people with Cystic Fibrosis aged 12 and older for a study of blood, sputum, and/or leftover fluid collected during your bronchoscopy to look at how your body responds to infection or inflammation.
Seeking intubated (tube placed in someone's throat to help them breathe) people for a study of an investigational device to improve their communication with caregivers.
Seeking men and women with either normal airways or airways that have been difficult to manage while under anesthesia for a study of a voice test might reliably predict people whose airways may be difficult to manage during an operation.
This is an observational study of patients with cystic fibrosis. Any patient diagnosed with cystic fibrosis can participate.
We are collecting blood samples from healthy controls and Systemic Lupus Erythematosus (SLE) patient samples to learn more about potential molecules that are responsible for the development of Lupus.
Seeking men and women with Active Systemic Lupus Erythematosus (SLE) to undergo testing of CABA-201, an Autologous CD19-specific Chimeric Antigen Receptor T cells,
Seeking men and women with opioid use and mental health disorders for a study of different combinations of treatments.
Seeking men and women 18-30 to help us better understand how the brain work in persons with anxious personalities.
Seeking men and women to be interviewed about their health and medication use for a study about long-term use of medications.
Seeking transgender patients who receive either hormone replacement therapy (HRT) alone or gender confirmation top-surgery in addition to HRT for a study of the impact of treatment.
Seeking veterans with post-traumatic stress disorder (PTSD) or PTSD symptoms for a study of an intervention to see if observing and caring for injured or orphaned wildlife at a wildlife rehabilitation center helps to reduce PTSD symptoms.
Seeking deaf adults and ASL users who is experiencing problems with alcohol use and trauma for an experimental intervention that we hope will reduce symptoms of addiction.
Seeking men and women with a medical or surgical pain for which they have been prescribed opioids for a study of how their body reacts to use of the opioids over time.
Seeking people aged 18 and older to be interviewed about their experiences and provide feedback for a study developing an experimental digital health tool for buprenorphine treatment.
People coming to the emergency room experiencing acute stress from a stressful situation will be asked to participate in a study of an investigational therapy for acute stress reaction.
Seeking people who have opioid use disorder and are planning to or have recently (within 6 months) started medical treatment for opioid use disorder for a study of an investigational device to treat cravings.
Seeking men and women who are or have taken buprenorphine for their opioid use disorder for a study developing a technology to assist in treatment.
Seeking men and women initiating treatment for opioid use disorder with extended-release bupenorphrine for a study of an investigational wearable sensor and mobile app to monitor cravings
Seeking male and female participants who are under 22 years of age at enrollment with newly diagnosed de novo AML (a cancer of the bone marrow) for participation in a study comparing standard chemotherapy to one or more investigational drugs.
Seeking parents of infants aged less than 1 year for a study of a device to help improve sleep quality for the baby and their parent.
Seeking families whose first language is not English with a child aged 5-10 years old who has been diagnosed with autism spectrum disorder for a study to understand autism diagnosis and treatment for families with diverse backgrounds.
Seeking women 18 years and older who are mothers to infants who had previously been hospitalized in the NICU at UMass Memorial Health within the last 6 months for a study about skin-to-skin contact (called "Kangaroo Care")
Seeking newborns who will be vaccinated against Hepatitis B for a study of a device to reduce pain during the injection.
Seeking boys aged 4-9 with Duchenne Muscular Dystrophy for a study of an investigational drug to prevent muscle damage.
Seeking women who are expectant or new mothers to participate in recorded interview sessions discussing experiences and opinions on weight and stigmas and a proposed intervention.
Seeking women in the Worcester area who are pregnant or have recently given birth for a study of a breastfeeding support app.
This study is collecting tissue and information from pregnant women who are having cesarean births to gain a better understanding of how the uterus functions.
Seeking pregnant women who have been diagnosed with gestational diabetes and plan on delivering at UMass Memorial for a study of the impact of timing of glucose tolerance testing following delivery on prevention of Type 2 Diabetes.
Seeking women who are less than 14 weeks pregnant for a study comparing screening for gestational diabetes at 14 weeks compared to the usual screening at 24-28 weeks of pregnancy
Seeking pregnant UMass Memorial healthcare patients with type 2 diabetes for a study comparing use of a continuous glucose monitor to multiple daily fingerstick monitoring.
Seeking women who are at least 24 weeks pregnant, will deliver at UMass Memorial, and either have insurance through Medicaid or are uninsured for a study to detect and manage hypertension in the first 6 months following delivery.
Seeking pregnant women with chronic hypertension, gestational hypertension or a history of hypertensive disorders of pregnancy for a brief survey of their experiences and approaches to healthy eating.
Pregnant women with either normal or high blood pressure sought for a study of the effects of high blood pressure during pregnancy. The study will assess whether future cardiovascular disease or serious pregnancy complications like preeclampsia can be better detected & prevented.
Pregnant women who are in their late 2nd to 3rd trimester who have high blood pressure are sought for a study to develop a screening test for preeclampsia in pregnant women. We will collect samples of your blood, urine, and saliva to see if we can detect levels of a protein that would help accurately predict who will get preeclampsia.
Seeking people who either have vitiligo or are closely related to someone who has vitiligo for a study of genetic factors that may impact the start or progression of vitiligo
Seeking healthy adult volunteers or adults who has had skin allergy patch testing in the past for a study of how anti-inflammatory therapies work in inflamed skin.
Seeking males and females with Vitiligo to learn more about whether they are more or less likely to have increased complications related to vision and hearing.
We are studying how skin diseases occur in the skin, including how immune cells choose to initiate disease as well as what causes them to enter the skin.
Seeking men and women who have previously had skin allergies or vitiligo for a study collecting skin and blood samples and conducting allergy patch testing.
Seeking people aged 2 and older with Dystrophic Epidermolysis Bullosa with confirmed mutation(s) of the Type 7 collagen (COL7A1) gene for a study of an investigational drug for wound healing.
Seeking people aged 12 and older whose moderate to severre hidradenitis suppurativa hasn't responded to anti-tumor necrosis factor (TNF) therapy for a study of an investigational drug.
Seeking men and women aged 18 and older who have been referred for skin patch testing of allergens for a study of an experimental micro needle patch test to diagnose skin allergy
Seeking adults or parents of kids aged 6 and older who use continuous glucose monitors (CGM) as part of their diabetes care for an online survey study to better understand skin conditions resulting from CGM use.
Seeking men, women, and children, 6 years and older who have a skin condition to provide data and specimens for laboratory studies.
Seeking men and women over 18 years of age who have been diagnosed with hidradenitis suppurativa (HS) for participation in a study looking utilizing Botox
Seeking people aged 6 and older with wounds caused by recessive dystrophic epidermolysis bullosa (RDEB) for a study of an investigational gene therapy.
Seeking people who need immediate care for frostbite for a study of an experimental method to rewarm frostbitten skin.
Seeking children under 18 years of age and healthy volunteers from 6 to 18 to study the skin immune system.
Seeking men and women with or without an inflammatory skin disease ( such as cutaneous lupus erythematosus, dermatomyositis, atopic dermatitis, alopecia areata, scleroderma, eczema, psoriasis, vitilago, or drug hypersensitivity) for a study to learn more about skin diseases and their response to light.
Seeking men and women 18 years of age or older who have had a stroke caused by bleeding in their brain to help determine is a new drug called recombinant factor VIIa (rFVIIa) can improve outcomes compared to a placebo when added to the standard care provided after a stroke.
Seeking men and women who will be admitted to the minimally invasive surgery service at UMass Memorial for a study of how walking after surgery helps with healing.
Seeking children who have been referred for outpatient ear surgery for a study comparing two drugs for managing pain and preventing emergence delirium when they are waking up from anesthesia following surgery.
Seeking men and women whose doctor has scheduled them for surgery to repair a colovesical fistula (CVF) for a study of the timing of foley catheter removal following surgery.
Seeking men and women aged 18-85 whose degenerative disc disease or spondylolisthesis requires spinal fusion surgery with bone grafting for a study of a synthetic bone graft.
Seeking men and women who will have surgery to repair pelvic organ prolapse surgery at UMass Memorial for a study comparing two different types of surgery on pain following the surgery.
Seeking men and women who will undergo a total knee replacement (arthroplasty) surgery at UMass Memorial for a study of an investigational device to monitor post-surgery recovery
Seeking men and women aged 65 or older who have been discharged from the hospital within the past month for a survey of their health and use of healthcare following their discharge from the hospital.
Seeking men and women, 18-80 years of age, who have experienced blunt head trauma with loss of consciousness for study of a new device to detect traumatic brain injury through blood testing.
Seeking men and women willing to use continuous glucose monitors and working with community health workers and clinical pharmacist to see if these can improve blood sugar control
Seeking adult men and women who have a wound that their medical provider has recommended be treated with a surgical procedure.